Radiological findings of porcine liver after electrochemotherapy with bleomycin

Histopathological findings in colorectal liver metastases after electrochemotherapy

Electrochemotherapy of colorectal liver metastases has been proven to be feasible, safe and effective in a phase I/II study. In that study, a specific group of patients underwent two-stage operation, and the detailed histopathological evaluation of the resected tumors is presented here. Regressive changes in electrochemotherapy-treated liver metastases were evaluated after the second operation ...

Electrochemotherapy with bleomycin - a resume of published clinical trials

Introduction Electroporation is characteristed by the use of short, high voltage pulses which transiently permeabilize the cell membrane. As electroporation can be used to introduce various molecules directly into the cell cytosol, an obvious use has been to introduce chemotherapeutic drugs directly into cancer cells (electrochemotherapy). Many chemotherapeutic drugs are lipophilic and enter ce...

Tumor blood flow modifying effect of electrochemotherapy with bleomycin.

BACKGROUND Electrochemotherapy combines administration of the chemotherapeutic drug, followed by application of electric pulses in order to increase drug delivery into the cells. The aim of this study was to determine the tumor blood flow modifying effect of electrochemotherapy with bleomycin and correlate it with its antitumor effectiveness and extent of tumor necrosis. MATERIALS AND METHODS...

The treatment of cutaneous and subcutaneous lesions with electrochemotherapy with bleomycin

topographic findings of the porcine cornea

the porcine eye is often used as an ex vivo animal model in ophthalmological research. it is well-suited for investigations concerning refractive surgery; however, corneal topography data are scarce. this study investigated the corneal topography and pachymetry of the porcine eye to provide further reproducible data. we evaluated freshly enucleated porcine eyes (n = 16) by performing computeriz...